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Central Dogma Central Dogma is first starts with the finding that the genetic information found in chromosomes is located on the DNA, and not the protein, as McCarty and MacLoed announced to the public in 1944. It was then also backed by the E. Coli

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Introduction

Nandita Natasha Naidu BioSc. 2 Dr. Re February 22, 2005 Central Dogma Central Dogma is first starts with the finding that the genetic information found in chromosomes is located on the DNA, and not the protein, as McCarty and MacLoed announced to the public in 1944. It was then also backed by the E. Coli experiment made by Hershey and Chase. Then chemist Erwin Chargaff discovered that the percent of DNA were equalities of A = T and G = C, which are now known as Chargaff's rules, which was then explained by the discovery of the double helix by Francis Crick and James Watson. RNA is the step between DNA and protein synthesis. ...read more.

Middle

Because of the double helix, it can separate into to DNA strands, and "new" nucleotides then match up with there corresponding nucleotide (T with A and G with C). These nucleotides then are connected to form the sugar-phosphate backbones, and are identical to the "old" double helix DNA strands. RNA polymerase is an enzyme that pries apart two strands of DNA and hooks together the RNA nucleotides. The RNA that results from the copying of the DNA nucleotides is messenger RNA. After RNA synthesis, translation occurs. Translation is the actual synthesis of a polypeptide, and it occurs under the direction of mRNA. mRNA is a copy of gene, which acts as a photocopy of a gene by having a sequence complementary to one strand of the DNA ...read more.

Conclusion

rRNA is the structural components of the ribosome, also has sequence complementarity's to regions of the mRNA so that the ribosome knows where to bind to an mRNA it needs to make protein from. snRNA involves in the machinery that processes RNA's as they travel between the nucleus and the cytoplasm. Proteins are arranged with 20 different amino acid that can be arranged in any order to make a polypeptide of up to thousands of amino acids long, their potential for variety is extraordinary. This variety allows proteins to function as exquisitely specific enzymes that compose a cell's metabolism. An E. coli bacterium , one of the most simple biological organisms, has over a 1000 different proteins working at various times to catalyze the necessary reactions to sustain life. ?? ?? ?? ?? Naidu 1 ...read more.

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