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Chemistry paper outline: Nicotine I. History and facts A. Naming and group

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Chemistry paper outline: Nicotine * I. History and facts * A. Naming and group * a. Solanaceae group of plants classified by it's nicotine which consists of plants such as potatoes, eggplants, tomatoe,etc. * b. most commonly associated with tobacco plants, found when biosynthesis happens * c. Named by the plant Nicotina tabacum * B. Key history * a. 1600's-1700's- Nicotine was introduced to Europe in tobacco and later brought to America, associated with god and later on evil. * b. 1800's-Scientists like Vauquelin and Poselt began studying Nicotine and discovered facts about it such as its weight, formula, structure, etc. * C.1900- Scientists began studying nicotine medical terms as how it can help and damage humans. * d. Many synthesis studies of nicotine occurred. ...read more.


Enters through absorption into the pulmonary capillary blood flow * b. The half life of nicotine inside is about 2 hours and is spread across human blood. * c. When in acidic environments, it is ionized and can't switch membranes easily, it can penetrate skin as well. * d. When inhaling nicotine it can reach the brain in around 10 seconds making it one of the most addictive forms of taking it. * e. Nicotine in the body is eliminated by metabolizing in liver, lung, and kidney. Excretion depends on pH and flow. * B. Reactions with nicotinic receptors * a. Nicotine acts and increases activity of nicotinic receptors in the nervous system. * b. mimics acetylcholine and depolarizes and opens ion channel. ...read more.


Certain myths about this treatment such as risk of cancer and failure are made but are mostly false. * V. Effects of Nicotine * A. Positive * a. Reduces anxiety, increase cerebral blood flow * b. Regulation of neuronal responses, also used as pain relief but has limitations of toxicities. * c. Also has been documented as an antipsychotic agent * B. Negative * a. withdrawal and acting on reward pathways along with addictive nature * b. Can cause nausea, vomiting and diarrhea. * c. Respiratory distress, hypothermia and has links to circulatory disease due to it spreading across the blood stream. Inhaling is the worst form of taking nicotine. * d. Weight loss also occurs because of loss of appetite and increased metabolism but it can be controlled as a positive outcome as well. Links http://nicotinefacts.weebly.com/history-of-nicotine.html http://www.chm.bris.ac.uk/motm/nicotine/E-historique.html http://www.bookrags.com/research/nicotine-woc/ http://www.sciencedaily.com/releases/2008/02/080229120651.htm http://www.jointogether.org/news/headlines/inthenews/2007/medical-uses-of-nicotine.html http://www.homedrugtestingkit.com/nicotine.html ...read more.

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