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Inducible Operon VS Repressible Operon - Genetic regulation is a process where certain proteins and other kinds of stimuli tend to cause a cell to express genes or not express them.

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Introduction

Inducible Operon VS Repressible Operon Genetic regulation is a process where certain proteins and other kinds of stimuli tend to cause a cell to express genes or not express them. The bacteria cell system is small system, but it carries out a lot of activities and must do so economically and efficiently, therefore actions of these genes must be regulated. There are two types of regulatory systems: inducible and repressible An operon is a cluster of genes that work together to form a polycistronic mRNA. It consists of structural genes, a promoter region, an operator region, and a regulatory gene. Structural genes code for the enzymes themselves. ...read more.

Middle

Both lac operon and trp operon have structural genes with related function are controlled by a single promoter/operator. 2. Both lac operon and trp operon have negative control regulation system controlled by repressor. There is a regulatory gene in the operon which encodes the repressor protein that attach to the operator to prevent transcription. Differences 1. In term of structure, the lac operon has three structural genes: lacZ, lacY, and lacA. Whereas the trp operon has five structural genes: trpE, trpD, trpC trpB and trpA. 2. In term of function, an inducible operon is generally involves in catabolic pathway. In lac operon, the function is to produce enzymes which break down lactose. ...read more.

Conclusion

Whereas the repressor produced by regulatory gene of a repressible operon is only an apo-repressor which have to combine with a co-repressor to form a holo-repressor in order to attach to the operator of the operon (trpR,,apo-repressor, combine with tryptophan, co-repressor, to form trpR- tryptophan holo-repressor) 5. An inducible operon is always OFF unless an inducer is present (lactose act as an inducer in lac operon). However a repressible operon is always ON unless a repressor is present (trytophan act as a co-repressor in trp operon). In conclusion, although both type of operon are regulatory systems in a bacteria cell, they have difference in term of their structures, functions and regulatory mechanisms. ...read more.

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