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Find out which antacid tablet works most efficiently using a technique called titration.

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Introduction

Aim: To find out which antacid tablet works most efficiently using technique called titration. Measurement: The measurements will use a titration to find what volume of hydrochloric acid an antacid tablet will neutralise. Theory: Our stomachs produce gastric acid to aid in digestion. This acid is mainly composed of hydrochloric acid that is secreted by cells of the stomach lining called parietal cells. Excessive secretion of this acid is common and can lead to many stomach problems such as gastritis, gastric ulcers and peptic acid disease. These disorders are treated by antacids, which reduce the amount of acid in the stomach by various means. Most antacids contain weak bases and they neutralize the stomach acids by reacting with them chemically. These antacids are best taken for occasional stomach problems and they act very rapidly to provide relief. Some of the most common bases that are used as antacids are: * Mg (OH) 2, magnesium hydroxide * Al (OH) 3, aluminium hydroxide * NaHCO3, sodium bicarbonate * CaCO3, calcium carbonate These chemicals are used because they are weak bases - strong bases would lead to the risk of damaging the stomach if too much was taken. Bases neutralize acids by reacting with them to produce a salt and water. This chemical reaction of a weak base with stomach acid can be written in the general form: Weak base + hydrochloric acid --> salt + water A specific example of this chemical reaction is: Mg (OH) 2 + 2 HCl --> MgCl2 + 2 H2O There are other forms of antacid that work by less direct means. ...read more.

Middle

I will crush the antacid tablet and add water to it. I will then add Indicators to find out which is the best one that shows the colour change. I will then add hydrochloric acid bit by bit and then shake the conical flask to speed up the process. So you can find out the exact amount of acid that was neutralized. Safety * Wear goggles when handling corrosive solutions etc. * Wear gloves * Take of blazers & wear aprons * Tuck in ties * Report any breakages or spills Fair test To make it a fair test I will: * Use the same amount of water each time. * Use the same amount of bromophenol blue each time. By using too much you increase the volume even by the slight mm therefore decreasing its accuracy. * Use the same volumes of acid each time from the burette. * Either uses a whole tablet or a crushed tabled. By using crushed you allow more surface area therefore more reactions. * It is essential that none of the powder be spilt or wasted as this may have major effects on the amount of hydrochloric acid to be neutralised. Preliminary To find if initial plan works and which indicator shows best color change and what concentration of hydrochloric acid gives best results. 1 2 Average Buirette Start 0.2 0.1 0.15 Buirette Finish 10 11 10.5 Titration volume of acid used 9.8 10.9 10.35 The results above are Hydrochloric acid with a concentration of 0.5 Mole. ...read more.

Conclusion

Evaluation By analysing by results the experiment was successful to its aim and provided enough information for further investigation. But to make my data more accurate I could have done a number of things differently. This experiment is not very reliable and accurate because you cannot find out the exact amount of acid the antacid can neutralize. * Used a stirring machine to accurately stir each solution until it was fully neutralized. * Some of the tablet was stuck to the basin so I could prevent it by using a different basin which wont let any crushed tablet to stay behind. This will allow my experiment to be more accurate because it is decreasing the volume of the tablet and alternating the calculations. * Used less bromophenol blue as is again alternates the calculation as it increases the solutions volume. The experiment could have faulted due to the amount of indicator in the solution, which can affect it. * The Evaporation of the water from the solution in high levels of heat. If the acid was not added soon enough, the solution would become a suspension, and not all of the antacid will be put to use. * If I were to repeat this experiment I would carry out each tablet between 3 and 5 tests and use a greater range of tablets. Conclusion I conclude The Rennie indigestion tablet was tested to be the best. This was because it was able to neutralize most volume in dm� of hydrochloric acid. I believe to be due to its greater mass over the other tablets. It would have contained a greater amount of alkaline so could neutralise more acid. Sandip Singh Mangat 10E ...read more.

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