• Join over 1.2 million students every month
  • Accelerate your learning by 29%
  • Unlimited access from just £6.99 per month
Page
  1. 1
    1
  2. 2
    2
  3. 3
    3
  4. 4
    4
  5. 5
    5
  6. 6
    6
  7. 7
    7
  8. 8
    8
  9. 9
    9
  10. 10
    10
  11. 11
    11
  12. 12
    12
  13. 13
    13

Investigating different types of aspirin and making aspirin.

Extracts from this document...

Introduction

Jide Aspirin Introduction In this aspirin course work I will be investigating different types of aspirin and making aspirin. I will be looking at all the process taken to make aspirin and all the ingredients in aspirin. I Will be: Extracting some salicylic acid (2-hyroxy benzoic acid) from willow twigs or bark. O C OH OH 2- hydroxy benzoic acid structure We will also be learning about TLC (thin layer chromatograph), and its uses to confirm the identity of compounds. Calculating percentage yield carrying out melting points. My assignment will be structured into four tasks: Task 1- a survey of aspirin containing medicines and the medical uses of aspirin. Task 2-extracting and identifying the active chemical in willow bark Task 3- comparing methods for making and purifying aspirin Task 4- analysing Task 1- a survey of aspirin containing medicines uses of aspirin Name of aspirin Adult/children Price Dose Ingredients Contra-indicators Ascriptin Children over the age of 12 �11.49 2 caplets every 4 hours while symptoms persist, not to exceed 12 caplets in 24 hours, or as directed by a doctor for arthritis therapy. Drink a full glass of water with each dose. Aluminum Hydroxide Dried Gel (80mg), Calcium Carbonate, Magnesium Hydroxide (80mg), Aspirin (500 mg) Do not use if taking a prescription drug for anticoagulation (blood thinning), diabetes, gout, or arthritis unless directed by a doctor. Antacids may interact with certain prescription drugs. If you are presently taking a prescription drug, do not take this product without checking with your doctor or other health professional. ...read more.

Middle

* Draw a base line using a graphite pencil on the palate. It should be just above the level that will be reached by the solvent in the beaker. Apply the solution the palate using a finely drawn out glass tube. * The spot formed by the solution should be as small as possible. This is because components that do not separate well, will tend to overlap if large spots are made. * Put the solvent in the beaker and cover it with cling film or a lid. Leave for 10 minutes to allow the atmosphere to saturate. Stand the plate in the beaker and replace the lid. * When the solvent front is near the top of the plate remove the plate. Mark the position of the solvent front. Set up for the thin layer chromatography Chromatography paper lid Solvent front Baseline beaker solvent Pure 2 hydroxy benzoic acid my sample of purified 2 hydroxy benzoic Acid Task 3- comparing methods for making and purifying aspirin O COOH C OH OH O C + (CH3 CO) 2O +CH3 COOH CH3 Salicylic acid ethanoic anhydride acetylsalicylic acid (vinegar) (2-hydroxbenzoic acid) (Aspirin) Method 1 Apparatus * 2-hydroxybenzoic acid * 100ml beaker * Ethanoic anhydride * Concentrated sulphuric acid * Distilled water * 250ml beaker * Vacuum filtration equipment (buchiner funnels, buchiner flasks, tubes and Filter paper) * Ethanol * Melting point apparatus Buchner funnel setup Weigh 5.0g of 2-hydroxybenzoic acid in a 100ml beaker. Add 10ml of ethanoic anhydride with care stir to dissolve the solid. Add 12 drops of concentrated sulphuric acid stir continuously to prevent charring. ...read more.

Conclusion

but I think that method 1 is the best method because you don't need to heat it up for that long and the sample is pure. Evaluation The literature value of aspirin is 1350C my sample for method 1 had a melting point of 1250C, which is quite close to the literature value, but it is not the same. Maybe this is because there were some impurities in my product or I did something wrong in the preparation stages. My sample for method 2 had a melting point of 1720C, which is very far from the literature value of aspirin this is mainly because there were some impurities in my sample making the melting point higher. Comparison with industrial processes of aspirin production In a factory were they make aspirin some of the processes that require precision, strength, time or knowledge are not done by humans they are done by machines or computers. The processes that are replaced by automation are: * The equipment and chemicals are transported on conveyor belts * Computers control the temperature * All of the processes that are done over night are done by computers * All of the filtration processes are done by computers * Controlling the batch reactor * Purification Some of the advantages of using machines and computers to do most of the work is: * They are more precise * More accurate than humans * They work none stop * They are more cheaper * They are more stronger * Faster * More accurate * No errors * More durable ...read more.

The above preview is unformatted text

This student written piece of work is one of many that can be found in our GCSE Aqueous Chemistry section.

Found what you're looking for?

  • Start learning 29% faster today
  • 150,000+ documents available
  • Just £6.99 a month

Not the one? Search for your essay title...
  • Join over 1.2 million students every month
  • Accelerate your learning by 29%
  • Unlimited access from just £6.99 per month

See related essaysSee related essays

Related GCSE Aqueous Chemistry essays

  1. Indigestion Tablets Investigation

    This would allow me to suggest which varieties are best for quick relief or relieving heavy indigestion problems.

  2. Determine the percent aspirin in an aspirin tablet and to compare this with the ...

    point is going to be lower therefore an indictor like methyl red which changes colour at 4.2 - 6.3 (from red to yellow) would produce the most accurate and precise results. Conclusion To summarise the points made in the discussion: * The results obtained from titrimetric analysis of aspirin show that the percent purity of one tablet is 96.47% pure.

  1. Recrystallization - choose the most appropriate solvent to obtain a successful recrystallization of benzoic ...

    Data and Result:- Weight of Benzoic Acid prior to recrystallization: 2.0 g Weight of filter paper: 0.53 g Weight of filter paper and recrystallized Benzoic Acid: 2.33 g Weight of recrystallized Benzoic Acid: 2.33 g - 0.53 g = 1.8 g Compare the melting point for both benzoic acid recrystallization procedures and compare the efficiency of each.

  2. Freezing Point Depression

    The freezing point is dependent on the number of solute particles in a solution. When sodium chloride dissolves in water it will dissociate into its 2 ions (Na+ and Cl-) therefore is will have the greatest effect on the freezing point of water and reduce it the most from 0�C to -4�C.

  1. Preparation of aspirin - The chemical background This is the overall reaction that ...

    The reverse of esterification is the breakdown of a ester by the addition of water. The reaction between water an ester is very slow, a catalyst is added to speed up the process. A catalyst is very effective for both directions of a reversible reaction, acid catalyses the reaction and alkalis, like sodium hydroxide.

  2. Analysing the ethanoic acid concentration in different types of vinegars.

    has boiled to virtual dryness I will remove the flame and stop collecting the distillate. I will then bung the conical flask to prevent evaporation of the ethanoic acid. Titration: I will now measure the concentration of acids in vinegars and distillates via the method of titration.

  1. SCIENTIFIC PRACTICAL TECHNIQUES

    AIM: To see if the culture is growing within an hour as checking it every 15 minutes for an hour. TASK 1(P4) The equipments used for this experiment is microscope, haemocytometer and a pippetor. RESULTS TABLE NUMBER OF SQUARES TIME NUMBER OF HOW MANY MICRO-ORGANIMS 16 15 100000 16 30 22500 16 45 320000 16 60 430000 Calculations cells/ml 1)

  2. Analysing aspirin tablets.

    The mixture was then cooled and transferred with washings to a 250 cm3 standard flask and made up to the mark with lime water. * Both Partners 8. We pipetted the hydrolysed solution into a conical flask. We titrated this against 0.10 mol dm-3 HCl using phenolphthalein indicator. 9.

  • Over 160,000 pieces
    of student written work
  • Annotated by
    experienced teachers
  • Ideas and feedback to
    improve your own work