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Sickle Cell Disease Research Project

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´╗┐Description Sickle Cell Disease (SCD) is caused by an irregular type of hemoglobin (hemoglobin is the oxygen carrying protein in red blood cells), called hemoglobin sickle or hemoglobin S. Hemoglobin S alters the shape of red blood cells (especially when cells are open to low oxygen levels). When hemoglobin S is deoxygenated, it tends to clump with other deoxygenated hemoglobin, interrupting the flow of blood to any given area of the body. When this happens an SCD patient is said to be in ?crisis? the patient can experience severe pain, organ damage, joint damage, various medical problems, and even stroke. Signs and Symptoms The signs and symptoms of SCD vary. Some people have minor symptoms, while others can have severe symptoms and often require hospitalization for treatment. The most common signs and symptoms of SCD are anemia (lack of red blood cells) ...read more.


A blood test known as Hemoglobin Electrophoresis is used to identify hemoglobin characteristics in the blood after birth. Other ways of diagnosing SCD include Chorionic Villus Sampling (CVS) or Pre-Implantation Genetic Diagnosis (PIGD). CVS involves taking a sample of chorionic tissue from the placenta and is then examined at a laboratory. PIGD involves removing eggs from a woman?s ovaries. These are then fertilised using sperm taken from her partner. The fertilised embryo can then be tested for SCD. If test results are negative, the embryo can then be implanted into the woman?s womb. Treatment Sickle cell anemia has no widely available cure. However, treatments can help relieve symptoms and treat complications. The goal of treating SCD is to relieve pain, prevent infections, and organ damage. The usual treatments for acute pain is fluids, medicines, and rest. Fluids help prevent dehydration, and medicine helps ease pain a patient will encounter. ...read more.


?World Sickle Cell Awareness Day? is June 19. This annual event celebrates the date in 2008 when the General Assembly of the United Nations implemented a resolution recognizing SCD as a public health concern. ?World Sickle Cell Awareness Day? provides an opportunity to increase understanding of SCD and how the disease affects individuals and families worldwide. Conclusion SCD is a disease that affects the hemoglobin in the body, and causes clots in blood vessels when deoxygenated. People diagnosed with SCD often live short and painful lives, although new methods of treatment have greatly enriched the lives of many SCD patients. SCD is becoming a more commonly recognized disease and events such as SCD Awareness day are greatly rising awareness. The future of this disease will be determined by the people, the more people who are affected by SCD and the more awareness about SCD, will cause an increased motivation in possibly finding a cure for SCD. ...read more.

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