Preparation of ear drops practical. Titration of NaHCO3

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Dominic Areago

Preparation of ear drops practical

Introduction

        Eardrops are preparations used for the treatment of various disorders of the ear. They come in numerous dosages and consist of many different ingredients depending on what they have been recommended for1. Over time the composition of eardrops have improved and been more tailor made to cover a large range of specific ear problems. The most common problem involving ears is earwax. Earwax is produced to keep the ear clean and to protect it from infections. Sometimes the production of it either becomes too much. These earwax problems can cause various conditions such as dizziness, hearing loss, irritability as well as loss of balance2. When eardrops are administered they break up large compacted pieces of earwax into smaller manageable clumps. As mentioned the composition of eardrops vary depending on the specific ear problem. This experiment is based around the accuracy of a prepared eardrop.

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Method

The method is devised into two separate sections:

Preparation of eardrops

  1. Weigh out 5 grams of NaHCO3 
  2. Add NaHCO3 to a volumetric flask then dissolve in 60ml of purified water.
  3. Measure 30ml of glycerol using a pipette.
  4. Add the glycerol to NaHCO3 solution
  5. Make volume of NaHCO3 solution to 100ml by using purified water. Shake once mixed

Titration

  1. Take 5ml of eardrop and then add 20ml of water.
  2. Place this in a conical flask.
  3. Add 2-3 drops of methyl orange to be an indicator
  4. Then ...

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