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Preparation of ear drops practical. Titration of NaHCO3

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Preparation of ear drops practical Introduction Eardrops are preparations used for the treatment of various disorders of the ear. They come in numerous dosages and consist of many different ingredients depending on what they have been recommended for1. Over time the composition of eardrops have improved and been more tailor made to cover a large range of specific ear problems. The most common problem involving ears is earwax. Earwax is produced to keep the ear clean and to protect it from infections. Sometimes the production of it either becomes too much. These earwax problems can cause various conditions such as dizziness, hearing loss, irritability as well as loss of balance2. When eardrops are administered they break up large compacted pieces of earwax into smaller manageable clumps. ...read more.


Results The results obtained from the titration are as follows: Volume in cm3 Trial Titre 1 Titre 2 Titre 3 Titre 4 Initial volume 50 50 50 50 50 Final volume 12.50 19.50 19.40 19.50 19.20 Total amount used 37.50 30.50 30.60 30.50 30.80 From the results it can be clearly seen that the trial titration was overshot. The four titre results all fell within 0.30 cm3 of each over, showing accuracy. The average of the four titres came to be 30.60 cm3. To calculate the molarity of NaHCO3 Using the formula Moles= Concentration/Volume The concentration is given at 0.1 M and the volume obtained is 26.60 cm3. By rearranging this equation, molarity can be calculated: 0.1 x 30.6 = 5.005(being the weight) ...read more.


Another contributing factor wound be the use of a weighing boat, to say all of the powdered NaHCO3 was added to the beaker with no grains left in the dish would be incorrect as it is not easy to ensure that the entire 5.005 grams entered the beaker. These minor details may have contributed to difference seen in the calculation and the amount actually weighed. Not withstanding differences may be caused by the accuracy of an individual when looking at markings on lab equipment. Discussion The mixture used in this experiment is just one of many mixtures used to make eardrops. Different eardrops require different amounts of ingredients, that where titrations come into importance. Pharmacists use titrations to ensure that the amount they believe to be measuring is actually present. ...read more.

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