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Pathophysiology of health and disease

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Introduction

Pathophysiology Practical Name: Jamie Williams Student Number: ST07001388 Course: Sport Biomedicine and Nutrition Module: Pathophysiology Pathophysiology of Disease In this practical write up I will establish the haematological indices of a patient's blood, in order to determine how healthy the individual is. We can establish what diseases the patient is suffering from or what diseases they may suffer from due to the symptoms they are showing. 'Pathophysiology is the study of the disturbance of normal mechanical, physical, and biochemical functions, either caused by a disease, or resulting from a disease or abnormal syndrome, or condition that may not qualify to be called a disease'. (Kumar, V et al). More formally, it is the branch of medicine which deals with any disturbances of body functions, caused by disease or prodromal symptoms. Hematology is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hermatology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases. The lab work that goes into the study of blood is performed by a Medical Technologist. ...read more.

Middle

A healthy level for the colour index is 1. The mean corpuscular hemoglobin concentration, or MCHC, is a measure of the concentration of hemoglobin in a given volume of packed red blood cell. It is reported as part of a standard complete blood count. It is calculated by dividing the hemoglobin by the hematocrit. A normal value is 32 to 36 g/dl. Sample A From looking at the results I have concluded that sample A is healthy. Firstly the RBC count falls in between the averages with a reading of 5.27 with the normal ranges from 4.5 - 6.5. Secondly his haematocrit count is at a healthy level with a reading of 48% and his Hb content of blood is also of a healthy level. Although his colour blood index is above the norm, anything usually above this suggests that they might suffer from anaemia; anaemia is a condition where you do not have enough haemoglobin in your blood. It can make you feel tired, breathless and faint. The most common type of anaemia is caused when there is not enough iron in the body. ...read more.

Conclusion

I can conclude then that sample c suffers from Polycythaemia Vera. Accuracy and Reliability Accuracy and reliability for results was brought about by ensuring great care was taken when handling the blood. The patient was made to feel as relaxed and at ease as possible by ensuring a qualified phlebotomist. The safety was at a maximum by ensuring everyone in the lab was wearing goggles and lab coats. Conclusion I have come to the conclusion that the only healthy patient is blood sample A. Blood sample B is deficient in Iron, and very likely to be suffering with anaemia. Whilst blood sample C is suffer from Polycythaemia Vera. Polycythaemia Vera is a rare medical condition that causes a high red cell count. Red cells make up the majority of blood cells. They transport oxygen through the body, so their main content is the oxygen-carrying protein, haemoglobin. PV is one of a group of diseases called myeloproliferative diseases (MPDs) where the cells that produce blood cells develop abnormally. Rarely, a high red cell count can also occur in the other MPDs - essential thrombocythaemia (ET) and myelofibrosis (MF). The main problem caused by polycythaemia vera is that the high number of red cells increases the blood's 'thickness' (viscosity). Blood flow to organs is reduced and, rarely, blood clots can form. ...read more.

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