A brief history of stress investigation

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A brief history of stress investigation

Hans Selye first started to investigate the issue of stress, even before he know that was what he was doing.  As with so many discoveries in the scientific community, they are often as a result of an investigation into something else, and in the case of Selye’s studies he was actually investigating the effects of hormones on rats.

He found that they were developing ulcers and greatly enlarged adrenal glands and could have easily concluded that the introduction of extra hormones into rats causes ulcers and enlarged adrenals.  

As a theory it appears initially a sound conclusion.  Therefore one could suggest that if you wanted rats not to have ulcers and enlarged adrenal glands then don’t give them extra hormones.

But scientists like to make sure that their conclusions are correct so they carry out checks to remove possible alternative causes of the discovered result.  Therefore he carried out a control study.  This means he injected another group of rats with saline (salt and water mix) with the assumption that nothing would happen as saline should have no effect on the rats metabolism.

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He found in fact that the rats suffered the same physiological alterations to those being injected with hormones.

The obvious conclusion is that it is the injection itself that is causing the physiological changes not the substance that is being injected.  Therefore the changed state was as a result of the rats’ response to being injected.

Any of you who are ‘needle phobic’ would have saved an awful lot of rats having to go through such experiments because you could have dramatically demonstrated that having a needle put into you will cause stress!

The word ‘stress’ ...

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