Arguments For And Against The Development of A Genetic Profile For All Members of Society

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All living organisms have DNA with the same chemical structure. The only difference between human and animal DNA lies in the order of base pairs. There are over millions of base pairs in each person's DNA so that every individual has a very different sequence. Using these sequences, any person could almost easily be identified solely by the sequence of their base pairs. DNA fingerprinting allows scientists to determine whether two DNA samples belong to the same person, relatives, or totally non-related people.

 Scientists use a small number of sequences of DNA that have been known to vary among individuals a great deal, and analyse those samples to get a certain probability of a match.  

A British scientist, Alec Jeffreys, first perfected the technique of using DNA samples to extract a unique marker—sometimes called a ”genetic fingerprint”—that ensured nearly absolute proof of identification. After the brutal rape and murder of two young women in the small English village of Narborough in 1986, police used Jeffreys’ DNA fingerprinting method to locate the culprit. (Rosen, C. 2010) Since then, DNA fingerprinting systems have played an increasingly important role in many aspects of human genetics, most notably in forensic and legal methods [Green, et al. (1991)].In more recent times, DNA fingerprinting’s impact on science, law and politics has been quite dramatic.

 One common practice in countries such as the U.S is that a genetic fingerprinting profile of a citizen who comes across any kind of “run-in” (Big or small) with the law is kept in a database. Keeping such a database of not only convicted criminals but that of people who are proven innocent has caused much controversy. (Rosen, C).

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DNA fingerprinting has been challenged in the past due to it validity in court cases because:

  • The probability of finding a match for a particular DNA pattern was found by multiplying the probability of the separate loci in a particular reference population. ( Which they could only get from a smaller database)
  • Samples may be contaminated because of bacterial growth in the sample before it was collected. Old samples may also break down and give inadmissible results. These samples may have extra bands or be missing bands.
  • Quality controlled labs were very few and as a result, led to ...

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*** A reasonable A-level report, which presents key arguments for and against recording everyone's DNA profiles in a database. Referencing is used, but the report lacks detail and could be improved by: 1)Relevant background information about how DNA profiles/fingerprints are generated 2)Some explanation of key terms like Loci/Genome etc/Short tandem repeat 3)Relevant images of genetic profiles to illustrate how they are unique 4)Sections to improve the report structure 5)Clear descriptions of how the reliability and validity of DNA profiles can be compromised if quality control does not prevent DNA breakdown and contamination