Cloning - The assualt on the sanctity of life

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Brian Lockyer                Grade 12 Life Sciences Research Task               1/03/08

Do you support the process of harvesting body parts and cloning methods?

The History of cloning

Cloning has been occurring in the natural world for thousands of years. A clone is just a time-delayed twin of another person or animal which results in both organisms acquiring the same set of genes.  Throughout history and most notably in the last hundred years huge strives have been made in the field of genetics, and they are bound to keep on happening.  The first person known to have successfully cloned an animal was Hans Dreisch in the late 1800’s.  Dreisch used sea urchins because they have large embryo cells and through his experiments he proved that genetic material is not lost during cell division.  In 1902, Hans Spemman successfully separated a 2 celled embryo of a salamander which eventually developed into an identical salamander.  Both these early breakthroughs paved the way for the modern concept of cloning.  

The next advance happened fifty years later in a laboratory in Philadelphia where a group of scientists successfully cloned a frog embryo.  This breakthrough was huge because the team did not simply break off a cell from the embryo of the frog; they removed the nucleus and replaced it for the nucleus of an unfertilized frog egg cell.  This was a huge breakthrough for modern day science as it was the first time that a nuclear transplant had ever been successfully conducted.  Nuclear transplants still occur today, however the method differs slightly.  In 1986 scientists from both the US and Britain claimed to have cloned the first mammal, big advances were made from those experiments including new insight and knowledge of how to keep tissue alive in laboratory conditions.

On July 5th 1996 Dolly was born, her birth marked arguably one of the greatest achievements of modern science.  It took scientists over two hundred attempts to clone her but eventually it all paid off although she did not live as long as hoped it is still regarded as the biggest ever breakthrough for scientists as well as a massive achievement for mankind.  The first mouse was cloned in 1997, she was named Cumulina as she was cloned from cumulus cells using traditional nuclear transfer.  By the end of 1998 over fifty identical mice had been successfully cloned.  As cloning technology has improved over the years so has the demand and applications for cloning in everyday life. For example recently an American couple has approached an American University is a bid to clone their eleven year old dog, they are spending over two million dollars to clone her.

The various types of cloning

There are three different types of cloning, embryo cloning, reproductive cloning and therapeutic cloning.

Embryo cloning

This type of cloning involves duplicating the natural process that results in twins or triplets being formed.  Cells are removed from a fertilized embryo and they are planted in other embryos and encouraged to develop, this procedure results in the formation of twins or triplets containing the exact same DNA.  This technique has mainly been utilized on animals.

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Reproductive cloning

Reproductive cloning is used to produce an identical replica of an existing animal.  Dolly was cloned using this technique, the procedure involves extracting DNA from an embryo and replacing the DNA is DNA from an adult animal.  The embryo is then implanted in the womb from where it develops into another animal. Reproductive cloning cannot ethically be used to produce a human clone due to the fact that some experiments on animals have produced defective specimens. 

Benefits

Opportunities for couples who are infertile or who cannot have children.

Negatives

Extremely low success ...

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