Professor Juma also highlights some remarkable benefits of GMO’s in the same article:
“The promise of the technology and evidence of its contributions to rural development around the world is serving as a source of inspiration for emerging nations to complement existing practices with agricultural biotechnology. Three African countries (South Africa, Egypt and Burkina Faso) have adopted genetically modified crops and are providing initial evidence of their long‐term implications. The scientific and technical community is being embolden by these developments and is working with governments to explore ways to build up the much needed capacity in these fields. Other African countries have started conducting field trials and plan to adopt biotechnology crops in the coming years.”[13]
Zoe Bianchi, author of several published senior biology teaching reference books with 19 years experience as a senior biology teacher tends to agree with Professor Juma, discussing the good that has come from GMO’s in an article entitled ‘The gm seed controversy’:
“In some cases, multinational seed companies have in fact waived their right to collect seed royalties, in a genuine attempt to help developing countries. An example is Syngenta’s research work with Golden Rice, a GM crop developed in 2000 in Germany and Switzerland.
Unlike normal rice, Golden Rice is high in beta-carotene, a precursor molecule in the production of Vitamin A. Developed using DNA from maize and a common soil microorganism, this rice promises to solve the global problem of Vitamin A deficiency, estimated by the World Health Authority in 2009 to occur in around 190 million children and 19 million pregnant women.
Syngenta has donated the most successful lines of its Golden Rice trials to the Golden Rice Humanitarian Board, along with all its research data and permission to use the seed for free. Other contributors to the board include the Bill and Melinda Gates Foundation, the UK government and the International Rice Research Institute.
The collaboration between Monsanto and the Governments of Kenya, Uganda, Tanzania and South Africa to develop drought tolerant maize, is another example of GM research aimed at reducing world hunger. Also funded by the Gates Foundation, seeds will again be made available to farmers free of royalty payments.” [18]
GM Foods in the world today
2011 was the 16th year of commercialization of biotech crops when growth continued after a remarkable 15 consecutive years of increases; a double-digit increase of 12 million hectares, at a growth rate of 8%, reaching a record 160 million hectares. GM crops are sold unlabeled in most parts of the USA; they have been for the past 14 years. Since then there have been no reported cases of death or hospitalisation as a result of eating GM crops.
The map and table on this page serve to confirm the reliability of this information and to also allow you, the reader, to fully come to terms with the immense growth that has happened in such a short period of time.
[15]
[12]
The risk
GM foods have been the victim of a lot of bad press; however this is not without cause: Dr Arpad Pusztai’s research, specifically on that of the Galanthus nivalis agglutinin (GNA) Potato and it’s affect on Rats, had detrimental consequences for GM food’s media image. His experiment was conducted at the Rowett Research Institute in Aberdeen (regarded as one of the most prestigious research centres for food and nutrition in the world) with a budget of £3,000,000 spread over 3 collaborating institutions headed by Dr. Pusztai [9] and it involved feeding GNA potatoes to rats. The GNA lectin is a “useful naturally insecticidal gene” [9] that Dr. Pusztai and his researchers hoped “would not harm ‘us’ as higher consumers of the same crops” [9] however the results of his experiment showed otherwise:
“Rats were fed on raw and cooked genetically modified potatoes, using unmodified Desiree Red potatoes as controls. One of the controls consisted of an unmodified Desiree Red potato spiked with the GNA snowdrop lectin.[4] Twelve feeding experiments were conducted, ten short-term (10 days) and two long-term (110 days).[9] Before the experiment Pusztai and his team said they expected there to be no differences between the rats fed modified potatoes when compared to rats fed the non-modified ones.[12][13] Their experiment however showed a statistically significant difference in the thickness of the stomach mucosa. The mucosa of rats fed raw or cooked potato modified with the GNA gene was thicker than that of rats fed the unmodified potato.” [8]
In August 1998 Dr. Arpad Pusztai was invited to talk on ITV’s “World in Action” about his work on the safety of GM foods and said the following: “If I had the choice, I would certainly not eat it until I see at least comparable scientific evidence which we are producing for our genetically modified potatoes.” [1] Which it is believed he was fired for. This became known as the Pusztai affair [7] and it validated a lot of the suspicions that the already concerned public had about GM crops and their potential health risks. This of course demonstrated by the global protests:
[3]
[5]
Alternate solutions
Those opposed to genetic modification mainly favour organic farming; an organic alternative to GM is cross-breeding - naturally pollinating different species of plants, however the success rate of this method is very small and it is also important to note that “Biotechnology, and in particular GMOs, are not per se more risky than e.g. conventional plant breeding technologies.” [14]
Even though GMO’s have relatively obvious economic benefits to third world countries the speed, precision and cost efficiency of the process is often scrutinised; however recent advances in the field of genetic modification mean that these issues may be solved.
Zinc Finger Nuclease (ZFN) technology is a high precision method of selecting and ‘cleaving’ genes from long strands of DNA. This allows the entire process of gene transduction to be carried out far more precisely – reducing cost and potential risk drastically.
The ability to precisely manipulate the genomes of plants, animals and insects has numerous applications in basic research, agriculture, and human therapeutics. Using ZFNs to modify endogenous genes has traditionally been a difficult task due mainly to the challenge of generating zinc finger domains that target the desired sequence with sufficient specificity. Improved methods of engineering zinc finger domains and the availability of ZFNs from a commercial supplier now put this technology in the hands of increasing numbers of researchers. Several groups are also developing other types of engineered nucleases including engineered homing endonucleases
To conclude I believe the future of genetic modification is a bright one, though there are many obstacles to over come the important thing is educating people about the real risks and potential benefits. With technology accelerating exponentially I’m sure in the next 20 years or so we can improve conditions in many third world countries economically and reduce mortality rates vastly. With the possibilities growing larger every day and world resources running thin it seems to me that GMO’s will be our saving grace.
BIBLIOGRAPHY:
1 – (Non-web source) “Seeds of Destruction”
Author: F. William Engdahl
Although quite biased, this source seems to be reasonably reliable. The author himself is a conspiracy theorist and author of only one other book which naturally makes me sceptical of his credibility, however references in the bibliography are confirmable and reliable sources, so although Engdahl has been very one sided in selecting his evidence, the sources from which he gets it are confirmed and trusted.
Ref. [8] [9] [10]
Pages used: 23
2 – (Web based)
Accessed: Feb 2012
en.wikipedia.org/wiki/Genetically_modified_crops
3 – (Image)
Accessed: Feb 2012
http://3.bp.blogspot.com/_P86w3jiXpHU/TI7eBYWhpFI/AAAAAAAAKkQ/5t_vOpXBLJU/s1600/Naturally+Yours+gm+food+protest+1.jpg
4 – (Web based)
Accessed: Feb 2012
news.bbc.co.uk/1/hi/uk/403784.stm
5 – (Image)
Accessed: Feb 2012
static.guim.co.uk/sys-images/Guardian/Pix/pictures/2012/3/8/1331234912784/AgrEvo-s-experimental-sum-007.jpg
6 – (Image)
Accessed: Feb 2012
geneticmodifiedfood.wikispaces.com/file/view/tomato.jpg/210372278/267x210/tomato.jpg
7 – (Web based)
Accessed: Feb 2012
en.wikipedia.org/wiki/Pusztai_affair
8 – (Web based)
Accessed: Feb 2012
en.wikipedia.org/wiki/Árpád_Pusztai
9 – (Video) Dr. Arpad Pusztai talks about his work on GM food safety
Part 1: youtube.com/watch?v=KNjMJIvI3RY Part 2: youtube.com/watch?v=HcjoL1-Z_E8
Uploaded: Apr 2011 Accessed: Feb 2012
Dr. Arpad Pusztai (8 September 1930) is a biochemist and nutritionist who spent 36 years at the Rowett Research Institute in Aberdeen, Scotland. He is a world expert on plant lectins, authoring 270 papers and three books on the subject. His doctorate in biochemistry was obtained from the Lister Institute and in 1988 he was made a Fellow of the Royal Society in Edinburgh. I personally believe this makes Dr. Arpad Pusztai an extremely reliable source; especially in this particular field.
10 – (Video) Scientists under Attack – Documentary trailer
Uploaded: Nov 2003 Accessed: Feb 2012
youtube.com/watch?v=ADNE1B2Rl5Y
11 – (Image)
Accessed: Feb 2012
geneticmodifiedfood.wikispaces.com/file/view/diagram%2Bgenetically%2Bmodified%2Bfood%2Bprocess.jpg/209505680/diagram%2Bgenetically%2Bmodified%2Bfood%2Bprocess.jpg
12 – (Image)
Accessed: Feb 2012
sitemaker.umich.edu/sec006group5/files/this_map.jpg
13 – (Web source)
Accessed: Feb 2012
belfercenter.ksg.harvard.edu/publication/21146/agricultural_biotechnology.html
14 – (Web source)
Accessed: Feb 2012
ec.europa.eu/research/biosociety/pdf/a_decade_of_eu-funded_gmo_research.pdf
15 – (Image)
Accessed: Feb 2012
www.worldfoodscience.org/images/foodsec_image2.jpg
16 – (Image)
Accessed: Feb 2012
en.wikipedia.org/wiki/File:Taq_polimerase.png
17 – (Image)
Accessed: Feb 2012
http://images.suite101.com/2140237_com_pcr_steps.jpg
18 – (Web source)
Accessed: Feb 2012
zoe-bianchi.suite101.com/the-gm-seed-controversy-a400841
19 – (Image)
Accessed: Feb 2012
http://www.anunews.net/blog/wp-content/uploads/2010/08/aa-frankenfood-cartoon-good-one1-300x262.jpg
20 – (Web Source)
Accessed: Feb 2012
sigmaaldrich.com/life-science/zinc-finger-nuclease-technology/learning-center/what-is-zfn.html
21 – (Web Source)
Accessed: Feb 2012
greenbio.checkbiotech.org/news/next_generation_biotechnological_plant_breeding_techniques
22 – (Web Source)
Accessed: Feb 2012
en.wikipedia.org/wiki/Zinc_finger_nuclease