The role of ATP in cells

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The role of ATP

ATP – adenosine triphosphate – provides an immediate source of energy for all cells in every living organism.

The diagram shows that one ATP molecule is made up of an organic base (adenosine) which is attached to a pentose sugar known as ‘ribose’. This sugar is then attached to three phosphate groups.

A lot of energy is stored in the ATP molecule and this energy is generated by the repulsion between the phosphate group and the negatively charged oxygen atoms which are bonded to each other. Most of the energy is stored in the bond of the last phosphate group and when energy is needed by cells, this bond is broken by a hydrolysis reaction catalysed by the ATPase enzyme. When one molecule of ATP is broken, adenosine diphosphate (ADP) and an inorganic phosphate group (Pi) are produced as well as about 30KJ of energy which is released (this value is measured under laboratory conditions but it is estimated that in cellular conditions, about 50KJ will be released). Although some of this energy is lost as heat, most of it is used by cells in their various biochemical processes. ATP is a more reliable source of energy as it is constantly being resynthesized; it is also a quicker process because only one bond needs to be broken to release energy which is unlike molecules such as glucose.

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Methods of synthesizing ATP

Energy can become available inside cells to aid the synthesis of ATP by two methods:

Chemical potential energy can be transferred from glucose molecules to ATP molecules. This happens in a process known as glycolysis in the Krebs cycle stages of respiration.

Process of chemiosmosis (diffusion of ions across a selectively permeable membrane) – it happens during aerobic respiration in mitochondria and light-dependent stage of photosynthesis.

Uses of ATP

Muscle contraction – actin and myosin filaments in the muscle fibres depend on ATP to function especially myosin which uses energy released from hydrolysis of ATP to ...

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