The Advantages And Disadvantages Of Treatments Of Heart Disease.

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The Advantages And Disadvantages Of Treatments Of Heart Disease.

Every year in the United Kingdom 270,000 people suffer heart attacks; along with this 2.1 million people suffer angina and other classic symptoms of heart disease (source 6). In this piece I am going to discus and in some cases challenge the modern technological, pharmaceutical and ethical issues related to heart disease.

The overwhelming cause of heart disease is atherosclerosis: the build up of lipid plaques (atheromas) in the coronary arteries; this in turn causes arteriosclerosis which is a thickening and hardening of the arteries and a decrease in elasticity (saurce1). Plaques have a protruding rough surface and so platelets stick to them and rupture. They then release growth hormones that cause the plaque to increase in size or release clotting factors that also cause the blockage to increase in size. Once this reaches a limit ischaemia sets in. This condition, in this instance, is the lack of O2, glucose and amino acids and reduced removal of H+ lactate and K+ ions to the mycrocardium; this decrease in pH produces a pain known as angina. If this lasts for an hour or more, the area may be permanently damaged (source 4). Death of heart muscle is known as myocardial infraction or more commonly, a heart attack. During ischaemia an arrhythmia called ventricular fibrillation can occur (source 1 & 4). This results in uncoordinated, weak contractions, a drop in blood pressure and sudden death if untreated. Other types of heart disease include; congenital heart disease: abnormalities that are present at birth, cardiomyopathy: affects manly heart muscle rather than the arteries, valular heart disease: abnormalities of the four valves that control blood flow in the heart (Source 2).

There are many factors that may contribute to some people having a higher chance of contracting heart disease compared to others; one reason for this is hereditary. Some people have a genetic predisposition, though unfortunate this is not uncommon, children inherit high LDL (low-density lipoproteins) cholesterol levels from their parents or even a lack of receptors which detect and remove LDL, this leads to a greater abundance of plaques which in turn may lead to heart disease (source 4 &1).

In other cases high blood pressure increases risk factors but this is only true when atherosclerosis and arteriosclerosis are already are both present in the coronary arteries. High blood pressure may damage the atheromas present or even the artery wall; this can cause clotting and lead to further health complications (source 1 & 9)

The condition diabetes with dyslipidaemia has been correlated with increased coronary heart disease. A common factor is seen as high LDL and triglyceride levels as found in the Prospective Cardiovascular Munster Study and similarly in the Helsinki Heart Study.

High cholesterol levels are the cause of atherosclerosis. High cholesterol levels are the result of a diet rich in saturated fats. LDL's deposit cholesterol in the cells of the body that are usually damaged, this forms plaques. Opposingly HDLs take cholesterol from the bodies cells and transport them for excretion (source 8).

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There are also some causes of heart disease which are self induced such as smoking, lack of exercise and poor diet which can lead to obesity. Smoking can have a deadly effect on the heart. Nicotine and other poisonous chemicals in a smoker’s bloodstream damage the lining of arteries including coronary arteries. Carbon monoxide, which is a poisonous gas, cuts down the amount of oxygen the blood can carry. So when you smoke, your heart has to work harder to get less oxygen (source 1, 2 & 5). Smoking also lowers vitamin levels such as Vitamin C, which arteries thrive ...

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*** This case study appears to have consulted a large number of references in order to discuss the treatment of heart disease but has failed to include a bibliography. It would benefit from focussing more on the title of the case study by discussing the differences in the treatments and their relative costs and benefits. To improve Collecting information It seems a good range of sources were used to provide information but unfortunately but these were not listed as references. There should be some discussion as to the confidence level that can be attached to the sources. Science content The background science is described in some detail but there is too much emphasis on the causes and detection of heart disease rather than the the subject of the case study which is the advantages and disadvantages of the treatment of heart disease. Comparing views The advantages and disadvantages need to be discussed in terms of cost, effectiveness and availability as well as the side effects of the treatment. This could be achieved by including some well annotated graphs , charts or tables. Conclusion and recommendations Information from different viewpoints needs to be identified not just as