• Join over 1.2 million students every month
  • Accelerate your learning by 29%
  • Unlimited access from just £6.99 per month

To determine the effectiveness of an indigestion tablet at neutralising acid.

Extracts from this document...


To determine the effectiveness of an indigestion tablet at neutralising acid. The stomach produces Hydrochloric acid, which provides a medium for the digestion of protein by the enzyme protease. An excess of acid can lead to indigestion, many tablets are on the market to help neutralise this excess acid, but all have different ingredients. I am to find out which commercially available indigestion tablet is most effective; Brand Name Dosage Active Ingredient Other Ingredients (non-active) Do not exceed... Rennie 2 tablets Calcium Carbonate 680mg Heavy magnesium carbonate 80mg Sucrose, glucose and saccharin 16/day Andrews Antacid 1-2 tablets Calcium Carbonate 600mg Heavy magnesium carbonate 125mg Malic Acid, sugar, magnesium stearate, talc, saccharin, sodium (22mg), sodium bicarbonate 12/day Tums Antacid Calcium carbonate 500mg Sugar, glucose, starch. Talc, magnesium stearate Setlers Antacid Calcium Carbonate 500mg Sucrose, dextrose, maize starch, talc, magnesium stearate, adipic acid Asilone Antacid 1-2 tablets Dimeticone 270mg Aluminium hydroxide 500mg Sucrose, sorbitol, French chalk, menthol Bisodol 1-2 tablets Sodium bicarbonate 64mg Calcium carbonate 522mg Light magnesium carbonate 68mg Saccharin, maize starch, sucrose, calcium stearate Remegel 1 tablets Calcium Carbohydrate 800mg Glucose, butylated hydroxyanisole, methanol Milk of Magnesia 2 tablets Magnesium Hydroxide 300mg The brands in bold are the six that I have chosen to investigate Equipment As there are six different brands available, the equipment list below may need to be multiplied by 5. ...read more.


On the second titration follow the same procedure, and as you approach the equivalent point titration value, begin to add the acid one-drop at a time. The equivalent point will be the value of pH 5 on the probe, as that is a safe value of acidity in the stomach. pH 7 could have been used, however, as this is testing the tablet, in the stomach it would only raise the value not neutralise the acid, therefore, I will use pH 5. Record the amount of HCl titrated in the table below. Continue until the titrations for each tablet are within 0.1cm3 of each other. Then record the average value in the table. Save the results from the pH probe. 1st tablet 2nd tablet 3rd tablet 4th tablet 5th tablet 6th tablet Brand 1 Initial value (cm3) Final value (cm3) (Final-Initial) Titre (cm3) 2 Initial value (cm3) Final value (cm3) (Final-Initial) Titre (cm3) 3 Initial value (cm3) Final value (cm3) (Final-Initial) Titre (cm3) FINAL AVERAGE TITRATION cm3 There are a number of variables that can be altered, but most must stay the same to make it a fair test. Independent variable(s) : Ingredients in indigestion tablets Dependent variable(s): pH value Controlled variable(s) ...read more.


Each tablet is alkaline e.g [H+] < [OH-] The HCl is acidic e.g [H+] > [OH-] Although they will not be neutralised, a neutral solution is [H+] = [OH-] = 10-7 dm-3 (where the number of protonated waters equals the number of hydroxyl anions.) The pH is defined as the negative of the logarithm of the hydrogen ion concentration. H+ + OH- -> H2O Or more correctly H3O+ + OH- -> 2H2O The alkaline solution/suspension contains millions of hydroxide ions, this number will gradually decrease as the acid containing hydronium ions are added. Eventually, a point will be reached when the number of hydronium ions is proportional to the number of hydroxide ions originally present, at this point the pH value will be five, and the end point will have been reached. Rennie 2HCl + CaCO3 --> H2O + CO2 + CaCl2 Andrews Antacid 2HCl + CaCO3 --> H2O + CO2 + CaCl2 Asilone Antacid 3HCl + Al(OH)3 --> 3H2O + AlCl3 Bisodol 2HCl + CaCO3 --> H2O + CO2 + CaCl2 Remegel HCl + CaHCO3 --> Milk of Magnesia 3HCl + Mg(OH)3 --> 3H2O + MgCl3 ilone Antacid he pH value will be five, and the end point will have been reached.number of hydrogenium as the hydonium ions a Chemistry Practice Plan March 2003 Camilla Marcus-Dew 12.7 Dr. Pratt ...read more.

The above preview is unformatted text

This student written piece of work is one of many that can be found in our GCSE Aqueous Chemistry section.

Found what you're looking for?

  • Start learning 29% faster today
  • 150,000+ documents available
  • Just £6.99 a month

Not the one? Search for your essay title...
  • Join over 1.2 million students every month
  • Accelerate your learning by 29%
  • Unlimited access from just £6.99 per month

See related essaysSee related essays

Related GCSE Aqueous Chemistry essays

  1. Marked by a teacher

    Enthalpy of Neutralisation.

    3 star(s)

    For example if I reacted 2 mol/l of NaOH with 2 mol/l Hydrochloric acid there will be an equal amount of ions that will react to form an exothermic neutralisation reaction likewise with 1 mol/l of each. But the 2 mol/l solution will produce the biggest temperature rise, as there

  2. Planning an Investigation To Determine The Effectiveness of Indigestion Tablets at Neutralising Excess Stomach ...

    Net price 20=28p * Hydrotalcite (Hoechst Marion Roussel) Tablets, hydrotalcite 500mg (low Na+) Net price 56=81p * Sodium Bicarbonate Tablets, Compound, BP Sodium bicarbonate 300mg. Contains about 4mmol Na+/tab Net price 50=56p * Maalox TC (Rhone-Poulenc Rorer) Tablets, co-maagaldrox 300/600 (magnesium hydroxide 300mg, dried aluminium hydroxide 600mg (low Na+))

  1. Find out which antacid tablet works most efficiently using a technique called titration.

    moles (13dp) Moles of NaHCO3 = mass/RFM = 0.064/84 = 0.0007619047619 moles (12dp) Equation for CaCO3 = CaCO3 + 2HCl >> CaCl2 + CO2 + H2O Moles of HCl that should be neutralised = 2 x moles of active ingredient = 2 x 0.00522 = 0.01044 moles Concentration of HCl to be used = 1M (1mole per dm3)

  2. Indigestion Tablets Investigation

    Therefore, as the sodium bicarbonate is warmed by being in hot acid it could break down into sodium carbonate, water and carbon dioxide. This carbon dioxide will add to the volume of gas being produced. "2NaHCO3 --> Na2CO3 + H2O + CO2" (page 169)

  1. Indigestion - find out the composition of tablets which are for indigestion and compare ...

    "IsoZymes" are made from premium plant sources. Plant based digestive enzymes work at any pH; meaning once it is in your stomach, it starts working right away. Animal based digestive enzymes do not begin to work until after your stomach pH drops very low; thus any person with hypochlorhydria (a

  2. Investigation of the carbonate - bicarbonate system

    H+ (aq) + HCO3-(aq) ..................................2 HCO3-(aq) H+ (aq) + CO3-2(aq)................................... 3 Carbon dioxide from the atmosphere dissolves into the solution and also achieves equilibrium as shown below; CO2 (g) CO2 (aq) .............................................4 The carbonic acid formed (H2CO3 (aq) ) from equation (1) is neutralized by the addition of base to for equation (2).

  1. Find out the percentage of citric acid present in lemon squash by using a ...

    And also safety glasses just in case there are any splashes. As our school desks are made of wood, which are varnished, the hot water could easily melt the tin and wearing layer of varnish on the table, for that we will put a few layers of news paper to

  2. Investigating antacids.

    Now place the glass beaker on the white tile and open the burette tap in order to clear it of any air bubbles thus removing any inaccuracies. Top up the burette as appropriate with HCl. Now place the conical flask containing the base onto the base of the stand and,

  • Over 160,000 pieces
    of student written work
  • Annotated by
    experienced teachers
  • Ideas and feedback to
    improve your own work