The factors affecting the development of coronary heart disease.

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Amy Bland

AS Human Biology Coursework Assessment

The factors affecting the development of coronary heart disease

  The heart is a muscle which needs a constant supply of oxygen and nutrients, which is carried in the blood through the coronary arteries. Heart disease is caused by narrowing of the arteries that run to the heart caused by fat and cholesterol deposits in the bloodstream, preventing the flow of blood. Coronary heart disease develops slowly and silently over years and it can go virtually unnoticed until it produces a heart attack.

   Artery disease is thought to begin with damage to the lining of the walls of the arteries known as Atherosclerosis. This is a progressive disease where the lumen of the arteries become narrower which can result in partial blockage of a coronary artery causing chest pain and cramp known as angina or even total blockage which may be fatal and result in a heart attack.

  Initially, atheroma occurs when fats from the blood plasma accumulate beneath the endothelium of the artery. The build up of fats produces a plaque which projects into the passage of the artery making it narrower. The plaque can become so large that it tears the endothelium and causes a blood clot which can travel in the blood and get trapped in an artery; this can be fatal as the vital nutrients are prevented from reaching the brain and lungs etc.

   Atherosclerosis is a disease that often starts at childhood and progresses over years; it progresses rapidly in older age. This is a factor of heart disease that cannot be prevented like gender, diabetes and hereditary, however it can also occur when a person has high levels of cholesterol which is a waxy, fat like substance that occurs naturally in all parts of the body and is used to produce many hormones. Too much cholesterol, however, deposits in the bloodstream, preventing the flow of blood. Cholesterol is a factor that can be controlled by appropriate diet; other uncontrollable factors are smoking, alcohol, blood pressure, obesity, inactivity and even stress. Each factor doubles the chance of developing CHD therefore a person with 3 of these risks, for example, is 6 times more likely of developing CHD.

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   When a person has an uncontrollable factor which increases their chances of developing CHD, it is advisable to minimise all controllable factors so that the chance is reduced.

   Firstly, old age greatly increases that chance of CHD with 80% of CHD suffers being 65 and over. Total cholesterol levels get higher over years which results in the build up in fats and narrowing of the arteries. However this can be minimised through cholesterol lowering drugs and appropriate diet. Lipid lowering drugs help lower the level of “bad” cholesterol in your body and raise levels of “good” cholesterol. Cholesterol ...

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