Normally, doctors will keep the film as a negative, so that areas that are exposed to, more light appear darker and the areas that are exposed to less light appear lighter. Harder materials such as bone, appear white, whereas softer materials appear black or grey. This means doctors can bring different materials into focus by varying the intensity of the X-ray beam.
Contrast media are used in order for soft tissues to appear more clearly. They are often used in conjunction with a fluoroscope. The fluoroscope allows x-rays to pass through the body onto a fluorescent screen creating a moving X-ray image. Doctors can use fluoroscopy to trace the passage of contrast media through the body. They are also able to record the moving X-ray image onto film or video.
Uses of X-ray machines
X-ray technology has mainly been used in the world of medicine but X-rays have also played crucial roles in a number of different areas including research involving quantum mechanics theory, crystallography and cosmology. In the industrial world X-ray scanners are used to detect flaws in equipment. And more commonly X-ray scanners are used for airport security.
Computerized axial tomography
What is Computerized axial tomography?
Computerized axial tomography (CAT) scan machines produce X-rays which is a powerful form of electromagnetic energy. A conventional X-ray image is principally a shadow. You shine a “light” on one side of the body, and a piece of film on the other side registers the silhouette of the bones.
Shadows give an incomplete picture of an objects shape. Imagine standing in front of a wall, holding a pineapple against your chest with your left hand and a banana out to your side with your right hand. Your friend is only looking at the wall, not at you. If there is a lamp in front of you your friend will see the outline of you holding the banana, but not the pineapple as your body blocks the pineapple, if the lamp is to your right your friend will see the outline of the pineapple, but not the banana.
The same thing happens in a conventional x-ray image. If there is a larger bone directly between the X-ray machine and a smaller bone, the larger bone may cover the smaller bone on the film. To be able to see the smaller bone, you would have to turn your body or move the X-ray machine.
In order for your friend to know your holding a pineapple and a banana, your friend would have to see your shadow in both positions and form a complete mental image. This is the basic idea of Computer axial tomography. In a CAT scan machine, the X-ray beam moves around the patient, scanning from hundreds of different angles. The computer takes all the information and puts together a 3-D image of the body.
How a CAT scan works
The patient lies down on a platform, which moves slowly through the tunnel in the machine. The X-ray tube is mounted on a movable ring around the edges of the tunnel. The ring also supports a range of X-ray detectors directly opposite the tube.
A motor turns the ring so both the X-ray tube and detectors orbit around the body. Each full orbit scans a narrow, horizontal slice of the body. The control system moves the platform farther into the tunnel so the tube and detectors can scan the next slice.
In this way the machine records X-ray slices across the body in a spiral motion. The computer varies the intensity of the X-rays in order to scan each type of tissue. Once the patient has passed though the machine, the computer combines all the information from each scan to form a detailed image of the body.
Uses of CAT scanners
CAT scanners are able to produce information very quickly which means there uses include scanning to find head injuries after a traffic or sporting accident and finding the precise location and size of a tumour which would not be provided by a conventional X-ray machine as it would not show enough detail.
Magnetic resonance imaging
What is magnetic resonance imaging?
The theory behind MRI is that the nuclei in certain atoms behave as small magnets. Both protons and neutrons in the nucleus have properties of spin. This spin may be in one of two directions. If there are even numbers of both protons and neutrons then there are equal numbers spinning in each direction so the effects cancel so there is no net spin. However, if there is an odd number of either protons or neutrons then the spins cannot cancel. The most important nucleus of this is hydrogen, which has one proton and no neutrons. Hydrogen is common in the body mainly as water. Nuclei with a net spin behave as magnets and have a magnetic ‘north-south’ axis.
Normally the magnetic properties of hydrogen atoms are not detectable, since the magnetic axes of the nuclei are randomly aligned, and the net effect is zero in all directions. If a strong magnet is applied, these nuclei will align themselves with the applied magnetic field, either in the same direction as the field or in the exactly opposite direction. There is a small preference for the same direction as the external field because the nuclei have slightly less energy than if they point in the opposite direction.
How an MRI scan works
The patient is placed in a strong magnetic field where it is most intense. In conjunction with radio wave pulses of energy, the MRI scanner can pick out small points inside the patient’s body. The system goes though the patient’s body point by point building up a 2-D image or 3-D model of tissue types.
MRI provides an unparalleled view inside the body. The level of detail is extraordinary compared with other imaging modality. By changing exam parameters, the MRI system can cause tissues in the body to take on different appearances. This helps the radiologist to determine if something seen is normal or not.
Uses of MRI scanners
It is found that large differences occur in relaxation times between tissue containing hydrogen bound in water molecules and tissue containing hydrogen bound with other molecules. This means that tissues with different water content will show up on the scan. It is particularly useful for looking at cancerous tissues, which are active areas of growth with a high blood flow hence a high water content, as they show up clearly against the background tissue where growth is not so fast. MRI scans of the brain show more detail than X-ray images because the grey matter has more water bound hydrogen than the white.
Ultrasound
What is ultrasound?
The normal range of hearing is from 20 to 20 000 Hz any frequencies above this range are called ultrasound. Typical frequencies used in medicine are in the megahertz range. Ultrasonic waves are emitted from a transducer, which is a device, which changes energy from one form to another. The transducer is a crystal which exhibits the piezoelectric effect, which is when a potential difference is placed across the crystal it, expands along one axis and, when the potential difference is reversed, the crystals contracts.
If an alternating potential difference is used, the crystal will oscillate like a loudspeaker. The reverse process is also true: if pressure is applied to the crystal, a small potential difference is formed across the crystal therefore the transducer acts both as a transmitter and receiver.
The basic ultrasound system works on a pulse echo technique using the equation:
Distance = Speed x Time
If the speed of sound in the different substances between the transducer and object is known and the time interval between the pulse and reflected signal can be measured, then the distance travelled by the pulse can be calculated.
How an ultrasound scanner works
There are three types of scanner the A scan, the B scan and the Doppler scan. These are used depending on the organ being scanned.
A scan
A pulse generator is connected to the ultrasound transducer and the time base of an oscilloscope. At the start of each sweep the pulse generator will send a pulse to the oscilloscope and at the same time trigger the transducer to send an ultrasound pulse into the tissue. When the ultrasound pulse hits a boundary between two tissue types some of the signal is reflected back to the receiver where it is amplified and shown as a second pulse on the oscilloscope screen. An A scan is a sequence of individual echoes due to reflections along one direction only.
B scan
To obtain an image, the B scan uses sensors attached to the probe which can define position and orientation of the organ in a two dimensional plane. The ultrasound beam is ‘swept’ across the plane and the image built up from the superimposition of a collection of A scans.
As this takes several seconds, any movements within the organ will degrade the quality of the image. This is overcome using ‘real time’ scanners of which there are two types phased array scanners and sector scanners.
The phased array scanner has small transducers, which are triggered individually very close together, with a small phase difference between each one. This creates a composite ultrasound scan, which does not need the sensors to define the orientation of the beam.
Sector scanners use one or more transducers, which are scanned mechanically across an arc of 60 degrees.
Phased array and sector scanners are hand held and scan fast enough for the images to be viewed as a ‘film’ on a television screen.
Doppler ultrasonography
Ultrasound can also be used in a completely different way to measure movement. When an object which reflects, or emits, waves is moving with constant velocity, a stationary onlooker will find that the frequency of the ways received is different depending on whether the object is moving towards or away from the onlooker. This is the Doppler effect. Doppler ultrasound devices measure the frequency changes in the ultrasound signal reflected from a moving object, the frequency change being proportional to the velocity of the object along the axis of the beam.
There are two types of Doppler system continuous and pulsed.
In a continuous Doppler system, a narrow beam of waves between 2 and 10 MHz is transmitted from one transducer while a second transducer acts as a receiver. Mixing the transmitted and received signals generates the Doppler signals.
A pulsed Doppler system gives range resolution that is defining a small volume at a given depth from which signals can be analysed. This can be done by transmitting pulses of ultrasound and opening a receiver gate for a short period between pulses. The delay in the gate determines the maximum distance between the transducer and the reflecting surface.
Uses of ultrasound
Ultrasound can be used for many things including finding the thickness of the eye lens, viewing the fetus during pregnancy and blood flow.
Endoscopes
What are endoscopes?
Using fibre optics endoscopes send light along a tube and return an image using total internal reflection. This means it is possible to view inside the body. The main advantage of endoscopes is that as it is a cold light source no heat is delivered inside the body.
How an endoscope works
Two different arrangements of fibres are used, called coherent and incoherent. Coherent are fibres arranged so that they have exactly the same relative positions at each end of the bundle then an image can be built up at the other end of the bundle from the object. Incoherent bundles are arranged in a random way and are cheaper to produce.
The endoscope consists of four parts:
- An incoherent bundle used to send light down the tube
- A coherent bundle which has a lens at the bottom end and is used to send reflected light back up the tube
- A channel for water which is used to clean the lens
- Another channel which allows liquids to be taken out of the body or biopsy probes to be put in the body to obtain small tissue samples
The tube is round and reasonably flexible. Almost all wavelengths of laser light can be passed along the endoscope except those that are in the infrared region as quartz in the fibres absorbs these wavelengths.
Uses of endoscopes
Endoscopes can be used along the tubes of the body, such as the trachea into the lungs and the oesophagus into the stomach and intestines. They can also be inserted through a small incision to view the internal parts of the body without the need of major surgery.
Conclusion
Without the use of physics the medical equipment, such as X-rays, ultrasounds and endoscopes, which I have researched above, would not exist. This would cause diagnosis of patients to be a long and complex procedure. This equipment has revolutionised medical practise and will continue doing so for years to come.
Bibliography
Medical Physics by Martin Hollins (university of bath. science 16-19)
www.howstuffworks.co.uk
Medical Physics (OCR)
Medical Physics by Jean A Pope