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Biology - Most effective way of reducing blood pressure

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The Problem - High Blood Pressure has always been the cause of Stokes and CHD (Coronary Heart Disease) leading to a Heart Attack or even CVD (Cardio Vascular Disease). It indeed is the biggest killer in this developed world. High blood pressure directly implicates on the blood vessels, the veins and the arteries. When blood pressure increases, it constantly damages the arteries, whereas arteries already have narrow lumens. When the artery wall gets damaged, by the high blood pressure putting an extra strain on the layer of cells (Endothelium), there are white blood cells moving to the damaged area, and they accumulate cholesterol from the blood. This cholesterol builds a deposit, known as atheroma. This is an inflammatory response. There also are calcium salts and fibrous tissue building up at the site, resulting in a hard swelling called a plaque on the inner wall of the artery. This hardens the artery. Those plaques case the artery to become narrower, which makes it more difficult for the heart to pump blood around the body, in other words, there is a rise in blood pressure plus there now is a positive feedback building up as the process continues. ...read more.


[http://www.medscape.com/viewarticle/452278_4] These data clearly state that Calcium Channel Blockers indeed lower blood pressure by a high amount at 34.5 mm Hg in systolic pressure and 17.5 mm Hg in diastolic pressure, yet more than the ACE-inhibitor which is also an anti-hypertensive drug, lowering blood pressure by reducing the synthesis of angiotensin II, a hormone casing vasoconstriction of blood vessels to help control blood pressure, this thus reduces vasoconstriction and lowers blood pressure. This data collected is pretty valid as they were both trialled around 3-4 years ago, the latest trials I could find. They are also highly reliable as the first data collected is from the NHS website increasing its reliability, as they help people suffering from illnesses hence would not produce false data. They are very appropriate as they show the exact values of the reduction in the blood pressure for hypertensive people and how it could help them decrease the risk of CVD/CHD. The methods provided above, as using Calcium Channel Blockers have now been proven to be one of the most effective drug in lowering blood pressure and they are very appropriate as the data shows that it leads to decreasing the risk of CVD or CHD by only decreasing the blood pressure and the other set of data ...read more.


Food with less salt should be consumed, as if you gain a lot of weight, you would lose the elasticity of the blood vessels as the fats in your body would minimise the contraction and expansion of the blood vessels, thus again increasing the blood pressure while the lumen or the arteries would be very tight. Healthy food would not only reduce the blood pressure, but you would have a healthier life with the right body mass for your body height. This method is totally risk free, and has been very successful in the previous trials carried out. Exercising is also a very good alternate to reduce blood pressure as it would burn the body fat and as stated previously, blood would be able to flow normally through the body. Highly developed countries intend to have a greater percentage of population suffering form hypertension as shown in the graph above as well. This is mainly because of stress which increases the heartbeat, making it to work more than normal, increasing the blood pressure thus increasing the risk of CVD/CHD. So Lifestyle plays a big role in the life expectancy of the human kind, as the world is developing , the Life expectancy in every country in decreasing because of the increasing risk of having a CVD/CHD via blood pressure and many other causes. ...read more.

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Response to the question

The candidate answers the questions very well. They cover a range of topics from the effect of high blood pressure to the type of drugs used, their effectiveness and some of the alternatives that exist.

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Response to the question

The candidate answers the questions very well. They cover a range of topics from the effect of high blood pressure to the type of drugs used, their effectiveness and some of the alternatives that exist.

Level of analysis

The candidate introduces and explains how high blood pressure contributes to CHD and strokes well. They also include a diagram which aids their explanation. To improve the structure of the essay the first section should be split into paragraphs by topic to make it easier to read. Their sources are not always the most credible and they should strive to evaluate better any information they have included. They evaluate the effects of the drugs that they show the action of in good depth and evaluate valid scientific articles. They also consider ethical, social and economical issues with the drug well. They evaluate alternatives to drugs well.

Quality of writing

Punctuation, grammar and spelling all to a good level. Tone of the piece is adequate. Format needs some work to split the chunks of writing into more manageable sections.

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Reviewed by skatealexia 16/09/2012

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