Describe how a protein molecule is organised into a specific 3 -D shape and how the shape of the protein can facilitate the recognition and binding of specific molecules.

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Describe how a protein molecule is organised into a specific 3 –D shape and how the shape of the protein can facilitate the recognition and binding of specific molecules.

Proteins are very large 3 dimensional macromolecules. They are very important as structural molecules in the cell, as energy sources, and most importantly as "enzymes"; Proteins are often called "polypeptides" because they are made of long chains of building blocks called "amino acids". As the protein molecules are constructed from varying combination of twenty types of amino acids, they variety of protein structure is never-ending. Protein is made up of its own sequence and number of amino acids, which is unique and is structured to perform a particular function. The unique shape of each and every protein determines the specific function of that protein. Proteins function by recognizing and binding to other molecules. There are four levels of protein structure- primary, secondary, tertiary and quaternary structure.

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Proteins have several levels of structure. The most basic is its primary structure. A protein's primary structure is simply the order of its amino acids.

Secondary structure of protein is the coiling and folding of the polypeptide chain and is caused by hydrogen bonding between the amino acids. This will result to the forming of a coil, fibril or pleated sheet pattern.

 Tertiary structure is the full 3-dimensional folded structure of the polypeptide chain. This 3D shape results from folding and coiling of amino acids. This shape is important for globular proteins like, enzymes, antibodies, ...

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