The majority of Mackintosh's work was created, with the help of a small number of patrons, within a short period of intense activity between 1896 and 1910. Francis Newbery helped Mackintosh to secure the prestigious commission to design the new Glasgow school of Art(now known as the Mackintosh Building); for Miss Kate Cranston he designed a series of Glasgow tea room interiors and the businessmen William Davidson and Walter Blackie commissioned large private houses, 'The Hill House' in Helensburgh and 'Windyhill' in Kilmacolm.
In Europe, the originality of Mackintosh's style was quickly appreciated and in Gemmany and Austria he received the acclaim that he was never truly to gain at home in Glasgow. In 1900, the Mackintoshes were feted in Vienna as a result of their contribution to the 8th Vienna Secession; this led to friendships with designers such as Josef Hoffmann and the commission to design the Wamdorfer Music Salon. In 1902, the Mackintosh Room at the Turin Intemational Exhibition was also enthusiastically received and he went on to exhibit in Moscow and Berlin.
Despite this success, and with his undoubted influence abroad, Mackintosh's work met with considerable indifference at home and his career in Glasgow declined. Few private clients were sufficiently sympathetic to want his 'total design' of house and interior and he was incapable of compromise.
By 1914 Mackintosh had despaired of ever receiving recognition in Glasgow and both he and Margaret moved to Walberswick on the Suffolk coastline where he painted many fine flower studies in water-colour.
In 1915 they settled in London and for the next few years, Mackintosh attempted to resume practice as an architect and designer. The designs he produced at this time, for textiles, for the 'Dug-Out' Tea Room in Glasgow and the dramatic interiors for Bassett-Lowke's house in Northampton show him working in a bold new style of decoration, using primary colours and geometric motifs. It was an output of extraordinary vitality and originality which went virtually unheeded in England.
In 1923, the Mackintoshes left London for the South of France where Mackintosh finally gave up all thought of architecture and devoted himself entirely to painting landscapes. He died in London, of cancer, on 10 December 1928.
Although Mackintosh died relatively unnoticed in Britain his work was not going to be forgotten. Today things are made based on his designs, which usually involved unopened flower buds or roses and stripes.