Research Proposal - Multiple Sclerosis (MS).

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Claire McNeill        Health Care Project

Research Proposal

M.S is the shortened version of Multiple Sclerosis. My reason for choosing this topic is that I am very familiar with M.S. My mother was diagnosed nearly ten years ago when I was only eight.

My mother’s life has completely changed since. Her lifestyle in general is different. No more late night watching T.V, no more golf, no more spring cleaning, basically everything she did before she is not capable of doing now. It is difficult for us a family to get through but we just take each day as it comes.

M.S is not a contagious disease. MS is a progressive, disabling illness that affects nerve cells in the brain and spinal cord. This is an autoimmune disease.

A fatty tissue called myelin surrounds and protects the nerve fibres but if the myelin is lost in specific areas scar tissue is left.

This scar tissue is ‘sclerosis’.

When the cycle is disrupted the electrical impulses are unable to send messages to the brain and this causes the symptoms of M.S. The disruption of nerve signals within the brain and spinal cord causes a variety of symptoms that can affect vision, sensation, and body movements.

People with M.S can expect to be diagnosed with one course of the disease, each of which might be mild, moderate or severe.

The four clinical courses of disease according to  2003 are:

  • Relapsing remitting MS — In this form of MS, there are relapses (episodes when symptoms suddenly get worse), followed by remissions (periods of recovery). Between relapses, the patient's condition is fairly stable, without deterioration.

  • Primary progressive MS — In this form, there is a gradual and continuous worsening of symptoms from the time when the illness first begins. There are no episodes of relapses and remissions.

  • Secondary progressive MS — In this form, someone who originally had relapsing remitting MS begins to suffer gradual deterioration in nerve function, with or without relapses. Secondary progressive MS ultimately affects 50 percent of people with relapsing remitting MS.
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The exact cause of M.S is still unknown although experiments are taking place at the moment to find out what the cause is.

According to the National Multiple Sclerosis Society 2003, researchers believe that the damage to myelin results from an abnormal response by the body’s immune system.

Autoimmune diseases tend to attack their own tissue.

I researched and found a few points on the  2003 website:

  • Most people with M.S are diagnosed between the ages of 20 and 50.

  • More women have M.S than men.

  • Studies indicate that ...

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