• Join over 1.2 million students every month
  • Accelerate your learning by 29%
  • Unlimited access from just £6.99 per month

Pathophysiology of health and disease

Extracts from this document...


Pathophysiology Practical Name: Jamie Williams Student Number: ST07001388 Course: Sport Biomedicine and Nutrition Module: Pathophysiology Pathophysiology of Disease In this practical write up I will establish the haematological indices of a patient's blood, in order to determine how healthy the individual is. We can establish what diseases the patient is suffering from or what diseases they may suffer from due to the symptoms they are showing. 'Pathophysiology is the study of the disturbance of normal mechanical, physical, and biochemical functions, either caused by a disease, or resulting from a disease or abnormal syndrome, or condition that may not qualify to be called a disease'. (Kumar, V et al). More formally, it is the branch of medicine which deals with any disturbances of body functions, caused by disease or prodromal symptoms. Hematology is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hermatology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases. The lab work that goes into the study of blood is performed by a Medical Technologist. ...read more.


A healthy level for the colour index is 1. The mean corpuscular hemoglobin concentration, or MCHC, is a measure of the concentration of hemoglobin in a given volume of packed red blood cell. It is reported as part of a standard complete blood count. It is calculated by dividing the hemoglobin by the hematocrit. A normal value is 32 to 36 g/dl. Sample A From looking at the results I have concluded that sample A is healthy. Firstly the RBC count falls in between the averages with a reading of 5.27 with the normal ranges from 4.5 - 6.5. Secondly his haematocrit count is at a healthy level with a reading of 48% and his Hb content of blood is also of a healthy level. Although his colour blood index is above the norm, anything usually above this suggests that they might suffer from anaemia; anaemia is a condition where you do not have enough haemoglobin in your blood. It can make you feel tired, breathless and faint. The most common type of anaemia is caused when there is not enough iron in the body. ...read more.


I can conclude then that sample c suffers from Polycythaemia Vera. Accuracy and Reliability Accuracy and reliability for results was brought about by ensuring great care was taken when handling the blood. The patient was made to feel as relaxed and at ease as possible by ensuring a qualified phlebotomist. The safety was at a maximum by ensuring everyone in the lab was wearing goggles and lab coats. Conclusion I have come to the conclusion that the only healthy patient is blood sample A. Blood sample B is deficient in Iron, and very likely to be suffering with anaemia. Whilst blood sample C is suffer from Polycythaemia Vera. Polycythaemia Vera is a rare medical condition that causes a high red cell count. Red cells make up the majority of blood cells. They transport oxygen through the body, so their main content is the oxygen-carrying protein, haemoglobin. PV is one of a group of diseases called myeloproliferative diseases (MPDs) where the cells that produce blood cells develop abnormally. Rarely, a high red cell count can also occur in the other MPDs - essential thrombocythaemia (ET) and myelofibrosis (MF). The main problem caused by polycythaemia vera is that the high number of red cells increases the blood's 'thickness' (viscosity). Blood flow to organs is reduced and, rarely, blood clots can form. ...read more.

The above preview is unformatted text

This student written piece of work is one of many that can be found in our University Degree Pharmacology section.

Found what you're looking for?

  • Start learning 29% faster today
  • 150,000+ documents available
  • Just £6.99 a month

Not the one? Search for your essay title...
  • Join over 1.2 million students every month
  • Accelerate your learning by 29%
  • Unlimited access from just £6.99 per month

See related essaysSee related essays

Related University Degree Pharmacology essays

  1. In this lab report I am going to investigate the neutralising behaviour of six ...

    However from Table Two ad from the speeds calculated in Table Three, it can be seen that the overall change in pH varies from one antacid to another. This means that even though all of the antacids are fast acting, their effectiveness varies, as they all cause a different overall change in pH.

  2. Free essay

    An investigation into the determination of Km and Vmax values for Alkaline Phosphatase

    PRELIMINARY METHODOLGY 1.0ml of buffer solution, 2.0ml of water and 0.5ml of substrate were placed, using a Gilson pipette, into a standard, clear, dry test tube. The Gilson pipette was used with care and precision, in accordance to the manual instructions, in order to obtain accurate measurements.

  1. Comparing the dissolution of tablets and capsules. The purpose of this experiment ...

    1.419 1.074 1.624 25 1.570 0.086* 0.582 0.117* 0.168 1.981 30 1.594 0.181* 0.680 1.723 1.925 0.189* 35 1.669 0.225* 0.930 1.176 1.565 1.461* 40 0.049* 0.117* 1.393 1.374 0.103* 45 0.104* 1.793 0.789 1.450 50 0.205* 1.021 1.397 55 0.127* 1.090 60 0.078 1.654 * indicate solution is diluted

  2. Schizophrenia - Physiology, Pathophysiology and Pharmacological Therapies

    nucleus, mitochondria, ribosomes etc, followed by the axons, which usually carries electrical message, axons are usually covered with myelin, which is made of fat, it helps to speed transmission of a nerve impulse down the axons, followed by the dendrites, which allows connection to other cells as they are arranged

  1. The aim of this experiment was to formulate and manufactured Aspirin 75mg tablets in ...

    Granulation improves both the compaction characteristics and flow properties of a mix and is able to prevent segregation of the constituents of the mix. However, wet granulation is not appropriate for water or heat sensitive drugs and this lead to poor chemical stability or unpredictable drug product performance.

  2. Determination of Molecular Weight via SDS Page Gel. The focus of this lab ...

    Bands are visible for unknowns 1,2,3 & 5. Unknown 4 did not appear in the gel. Unknown 1 displays a band at around 35 and 25 kDa. Unknown 2 displays a band at 70 and 55 kDa, Unknown 3 displays a band at 35 kDa. Two bands are observed for unknown 5, one at 35 kDa and other at 98 kDa.

  1. Pharmacology. The use of co-beneldopa and selegiline in the treatment of Parkinsons disease

    Most drugs are given orally and enter the blood stream by passing through the gut wall (Neal, 1992). Most drugs are recognised by the liver as a toxin and are broken down into metabolites (Campbell, 2011). First pass metabolism is when the strength of a drug becomes reduced before they can be circulated throughout the entire system satisfactorily (Disease.com, 2010).

  2. Analysis of 3 Unknown Chemicals

    Acetyl Chloride Test Evaluation of heat Indicates an alcohol Not much heat. Figure 13. The IR spectrum for unknown #35C. Table 10. The peaks obtained during from the IR and their corresponding functional groups for unknown #35C. Peak Functional Group 3335.9 -OH 1678.0 C6H6 3017.5 Csp2 Figure 14.

  • Over 160,000 pieces
    of student written work
  • Annotated by
    experienced teachers
  • Ideas and feedback to
    improve your own work