Gene Technology

Genetic modification

Over 20 years ago it was discovered that genes, and parts of genes, could be extracted from DNA using protein "scissors" then copied, or cloned. 

The gene could then be equipped with genetic "switches" to turn it up or down and inserted back into a living organism. This is the basis of genetic modification. It allows the sequences of genes to be determined.

Transferring single genes between different plants and animals, turning existing genes up or down, or removing a gene from its original position and placing it in a new position in the same organism are all referred to as genetic modification (GM). The terms genetic engineering (GE) or genetic manipulation also mean the same thing.

Plants, animals or microbes which have a new gene inserted into them are called genetically modified organisms (GMOs) or transgenic. The modified gene belongs to the new host but its sequence is altered for example, on the basis of specific information gleaned from studies of other organisms.

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DNA sequencing

DNA sequencing is the process of determining the exact order of the chemical building blocks (bases) that make up DNA. It is a laboratory procedure that involves first breaking down the DNA into short pieces, followed by separating the individual fragments using a technique called gel electrophoresis. A bar code pattern of the DNA pieces is produced which can then be read by computer.

An enormous volume of information on the genetics of organisms is being generated using this technique and is providing computer experts with a great challenge in handling the data.

Human Genome Project

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